Alcoholysis of Polycarbonate with Benzophenone Derivatives in Twin Screw Extruder.

Continuous Granulation with a Twin-Screw Extruder

Wet granulation in a twin-screw extruder: implications of screw design.

Wet granulation in twin-screw extrusion machinery is an attractive technology for the continuous processing of pharmaceuticals. The performance of this machinery is integrally tied to its screw design yet little fundamental knowledge exists in this emerging field for granulation to intelligently create, troubleshoot, and scale-up such processes. This study endeavored to systematically examine t...

Modeling of Transport Phenomena and Melting Kinetics of Starch in a Co-Rotating Twin-Screw Extruder

A mathematical model was developed to simulate fluid flow, heat transfer, and melting kinetics of starch in a co-rotating intermeshing twin-screw extruder (TSE). The partial differential equations governing the transport phenomena of the biomaterial in the extruder were solved by a finite element scheme. For validating the model, the predicted product pressure, bulk temperature at the entrance ...

Sequential calculation of torque in procedure of twin screw extrusion

The drug making resreach has accentuated on extrusion technology for a long time. The advance of drug bioavailibility, bead manufacturing and granulation is assured by extrusion procedures. There are also diverse effects in resereches with respect to the use of process understanging as a tool in quality management. Many initiatives of FDA such as PAT and QBD are getting accepted. In this survey...

Enzymatic hydrolysis of steam exploded corncob residues after pretreatment in a twin-screw extruder

A modified twin-screw extruder incorporated with a filtration device was used as a liquid/solid separator for xylose removal from steam exploded corncobs. A face centered central composite design was used to study the combined effects of various enzymatic hydrolysis process variables (enzyme loading, surfactant addition, and hydrolysis time) with two differently extruded corncobs (7% xylose rem...